At Typeone, we empower
the future of regenerative medicine
by mastering collagen science.
At Typeone, we empower
the future of regenerative medicine by mastering collagen science.
We are dedicated to developing and manufacturing advanced biomaterials from raw collagen to certified medical devices serving as both a trusted CDMO partner and a provider of innovative, clinically proven products.
Through deep scientific expertise, regulatory excellence, and a commitment to high-quality manufacturing, we support our partners worldwide in transforming biomaterial innovation into therapeutic solutions for dermatology, orthopedics, wound care, and beyond.
Our mission is to bridge the gap between cutting-edge research and real-world medical applications delivering safe, effective, and transformative collagen-based technologies that improve lives globally.
Deep with collagen,
The Story of Typeone:
From innovative startup to leader in the biomedical sector, TypeOne has charted a path of constant growth, driven by scientific excellence and commitment to innovation. Today, our mission is to empower the future of regenerative medicine through mastery of collagen science.
We dedicate ourselves to the development and production of advanced biomaterials from raw collagen to certified medical devices serving both as a reliable CDMO partner and as a provider of innovative and clinically proven products.
Thanks to our deep scientific expertise, regulatory excellence, and forward-thinking vision, we continue to redefine the boundaries of regenerative medicine to improve the lives of patients worldwide.
Main equipment and facilities
ISO8 Clean Room
Ultra-controlled 90m² environment with advanced air filtration systems. Ensures optimal conditions for sterile production.
Purified Water
Production System
500L/h capacity with reverse osmosis technology. Provides highest quality water for production processes.
Rotary Atomizer
5.0L/h productivity with micrometric precision. Transforms liquid solutions into finest powders through high-speed rotation.
Powder Filling Machine
180 pieces/hour capacity with high-precision dosing. Automates the packaging process with integrated quality control.
System certifications
Our certifications guarantee controlled processes
and reliable products.
Every phase of production follows rigorous quality protocols verified by independent certification bodies.
Certified Excellence
International standards recognized worldwide
ISO 13485:2016
Quality management specific to medical devices
ISO 9001:2015
Quality management system for all processes
Team
Luca Salvatore
Co-Founder/COO
Materials Engineer, he brings over a decade of experience as a Senior Researcher at the Department of Innovation Engineering, University of Salento, where he specialized in developing advanced materials and innovative solutions for bioengineering. His work focused particularly on collagen, bioactive scaffolds, and drug delivery systems for Advanced Therapies.
Since co-founding Typeone in 2011, he has played a key role as Site Manager and Chief Technical & R&D Officer, overseeing the design, development, and certification of medical devices in the field of Regenerative Medicine. His efforts have supported applications in aesthetic surgery, orthopaedics/traumatology, and wound care.
He now serves as the company’s Chief Operating Officer, continuing to drive innovation and operational excellence across all areas of the business.
Cosimo Saponaro
Co-Founder/VP
Co-founder of Typeone Biomaterials and Vice Chairman of the Board, he brings nearly 30 years of experience in the medical device industry.
His core expertise lies in scaling up innovative ventures – both technologically and organizationally – within highly regulated environments.
Throughout his career, he has successfully led industrialization and operational growth initiatives across a range of sectors, including vascular surgery, hybrid prosthetic technologies, gastrointestinal health, and collagen-based medical devices.
He has collaborated with leading international companies and large-scale organizations, consistently driving forward the development and commercialization of advanced healthcare solutions
Alfredo Spadavecchia
PRRC, RA/QA Manager
After earning a degree in Biomedical Engineering, he began his professional career in the biomedical sector, with a particular focus on medical devices.
He is an expert in CE Marking, ISO 13485, FDA 510(k), and Quality Management Systems in compliance with ISO 13485, FDA 21 CFR 820, and other international regulations.
Since 2013, he has further expanded his expertise with specialized knowledge in sterile medical devices, with a particular focus on substance-based medical devices and their special manufacturing processes.
Alessandro Sannino
Scientific Advisor
Professor of Materials Science, Rector’s Delegate for Research at the University of Salento, Italy, Visiting at MIT, Cambridge (MA). Author of more than 200 peer reviewed papers and 40 patents in the field of Polymers for Biomedical applications.
Got the approval of more than 50 Ethical Committees of primary International Hospitals for tens of human studies on his patented products, and FDA approval for an Rx product. Founder of Gelesis Inc, a Biotech in Boston and Calimera (Lecce), with a cumulative fund raising over 400M USD, and listed at NYSE (Wall Street).
As founder of Siryo SpA, an early stage investment fund in the field ‘One Health’, invested 30 M euro in 8 start-up.
Davide Fiscella
Business Development Advisor
Davide is a seasoned MedTech Advisor with over 20 years of international experience in the medical device industry.
He has held key commercial and strategic roles within various private multinational organizations—including device manufacturers, component suppliers, and distributors—across Europe, the USA, the Middle East, Africa, and Australia.
His career began in clinical product support within operating theatres and evolved through strategic marketing and commercial leadership, contributing to the success of numerous product launches and market expansions. Davide has worked across a range of therapeutic areas, including cardiovascular, critical care, in vitro diagnostics etc. He also gained valuable B2B experience by managing complex supply chain projects on specialty plastics for the medtech industry, helping drive double-digit growth for a European business unit. He is Founder and partner of advisory firms for the Medtech Industry and Partner of Private Equity Advisory organizations.
Davide holds a Master of Science in Biomedical Engineering from Politecnico di Milano. Born and raised in Sicily, he now lives in Bergamo with his wife and daughter.
Maria Lucia Natali
Production Manager
Materials Engineer – Ph.D., she started her professional career at Typeone, where she developed expertise in biomaterials for biomedical applications, with a particular focus on collagen and medical devices.
She played a significant role in the development and validation of manufacturing processes, as well as in the design and management of the company’s quality system, certified according to ISO 13485 standards.
She currently works as Production Manager at Typeone Biomaterials S.r.l., where she leads the management and optimization of production processes, ensuring operational efficiency, product quality and regulatory compliance. With an analytical mindset and a strong problem-solving approach, she actively contributes to the company’s continuous improvement and growth, guiding her team toward the achievement of ambitious goals.
Nunzia Gallo
R&D Advisor
Biotechnologist – Ph.D., researcher in the biomaterials sector for biomedical applications since 2017. She is an expert on extraction and processing processes of advanced materials of natural and synthetic origin, as well as about fabrication/characterization techniques of micro- and nano- structured systems.
She contributed to several research Projects, and collaborated with Companies and Research Institutions.
The results of her research activities were presented in various contexts, such as national and international conferences, besides being published on journals with a bio-engineering profile or patented. She is founder editor, guest editor and reviewer for several journals.
Chiara Kodra
R&D Biotechnologist
Pharmaceutical Chemist – With a background in pharmaceutical sciences, she has developed a strong interest in biomaterials and the potential of collagen-based technologies for biomedical applications.
At Typeone Biomaterials S.r.l., she applies her knowledge to research and development activities focused on the creation and improvement of collagen-derived materials and innovative biomedical products.
Within the Research and Development Department, she contributes to the design, testing and advancement of new product solutions, supporting the company’s commitment to innovation, quality and continuous progress in the field of biomaterials.