Discover the science behind
natural regeneration
Discover the science behind natural regeneration
Linerase – Bioactive collagen
for advanced skin biostimulation
Linerase is a next-generation biorevitalization treatment based on pharmaceutical-grade Type I collagen, designed to stimulate the skin’s natural regenerative processes.
Developed and manufactured under stringent quality standards, Linerase delivers safe, progressive, and clinically visible results in both aesthetic and dermatological practice.
Why Linerase?
Scientifically proven, naturally effective.
Bioactive Type I Collagen
Linerase is formulated with purified, native Type I collagen—the same type found abundantly in healthy skin. It serves as a physiological signal to stimulate fibroblasts, restoring structure and volume through a natural remodeling process.
Targeted intradermal action
Once injected intradermally, Linerase is gradually degraded by matrix metalloproteinases (MMPs) naturally present in the skin’s extracellular matrix. This enzymatic breakdown produces bioactive collagen peptides that act as signaling molecules, recruiting fibroblasts and initiating neocollagenesis. The result is a cascade of biological activity that enhances dermal density, elasticity, and hydration.
Dual Benefit: local and systemic impact
Degraded collagen peptides and amino acids—especially hydroxyproline-rich fragments—can enter systemic circulation via blood and lymphatic pathways. While their primary action remains localized, these byproducts may also support systemic protein metabolism, contributing to overall skin and tissue health.
Biocompatible and resorbable
Linerase integrates smoothly into the dermal matrix without triggering fibrosis or foreign body reactions. It is fully resorbed by the body over time and metabolized into beneficial amino acids such as glycine, proline, and hydroxyproline, all vital to tissue repair and antioxidant function.
Visible and sustainable results
The stimulation of endogenous collagen results in progressive improvements in skin texture, firmness, and tone. Clinical studies report visible outcomes within weeks, with continued enhancement after repeated treatment cycles.
Engineered and manufactured for excellence
As the original manufacturer, we ensure that every batch of Linerase meets rigorous pharmaceutical and safety standards. Our production technology preserves the collagen’s triple-helix structure, optimizing its biological effectiveness and compatibility with skin tissue.
Bioactive Type I Collagen
Linerase is formulated with purified, native Type I collagen—the same type found abundantly in healthy skin. It serves as a physiological signal to stimulate fibroblasts, restoring structure and volume through a natural remodeling process.
Targeted intradermal action
Once injected intradermally, Linerase is gradually degraded by matrix metalloproteinases (MMPs) naturally present in the skin’s extracellular matrix. This enzymatic breakdown produces bioactive collagen peptides that act as signaling molecules, recruiting fibroblasts and initiating neocollagenesis. The result is a cascade of biological activity that enhances dermal density, elasticity, and hydration.
Dual Benefit: local and systemic impact
Degraded collagen peptides and amino acids—especially hydroxyproline-rich fragments—can enter systemic circulation via blood and lymphatic pathways. While their primary action remains localized, these byproducts may also support systemic protein metabolism, contributing to overall skin and tissue health.
Biocompatible and resorbable
Linerase integrates smoothly into the dermal matrix without triggering fibrosis or foreign body reactions. It is fully resorbed by the body over time and metabolized into beneficial amino acids such as glycine, proline, and hydroxyproline, all vital to tissue repair and antioxidant function.
Visible and sustainable results
The stimulation of endogenous collagen results in progressive improvements in skin texture, firmness, and tone. Clinical studies report visible outcomes within weeks, with continued enhancement after repeated treatment cycles.
Engineered and manufactured for excellence
As the original manufacturer, we ensure that every batch of Linerase meets rigorous pharmaceutical and safety standards. Our production technology preserves the collagen’s triple-helix structure, optimizing its biological effectiveness and compatibility with skin tissue.
Mechanism of action:
collagen that triggers regeneration
Following intradermal injection
Collagen is recognized and enzymatically processed by the skin’s matrix metalloproteinases.
Resulting fragments bind to specific receptors on fibroblasts, initiating a regenerative response.
These cells increase production of new collagen, elastin, and extracellular matrix proteins.
Some peptides and amino acids enter systemic circulation, supporting broader skin health.
Metabolites are safely processed and excreted via the liver and kidneys.
This mechanism ensures both aesthetic and physiological regeneration, aligning with the skin’s natural renewal pathways.
Trusted by Experts, Backed by Science
Elevate Your Practice
Offer your patients more than just visible change
give them a solution rooted in regenerative science.
Offer your patients more than just visible change—give them a solution rooted in regenerative science.
Contact us to learn more about clinical training,
distribution opportunities, or medical documentation.
Contact us to learn more about clinical training, distribution opportunities, or medical documentation.